Severe Asthma ToolkitSevere Asthma Toolkit
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  • What is Severe Asthma?
    • Overview
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      • Travelling with Monoclonal Antibodies
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      • Obesity
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  • Living with Severe Asthma
    • Overview
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  • Establishing a Clinic
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  • Paediatrics
    • Overview
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Questionnaires

Home Diagnosis & Assessment Questionnaires
Questionnaire

Questionnaires may be useful to document a patient’s asthma symptom control and quality of life at initial presentation and changes in response to treatment.

Symptom control

Several questionnaires are useful to assess a patient’s symptom control in severe asthma. Three common questionnaires are listed in the table below. These questionnaires were developed as a measure of asthma control in the general asthma population, but are frequently used to assess asthma control in severe asthma.

The Asthma Control Questionnaire (ACQ-7) is commonly used in research and clinical practice, but shortened versions (ACQ-5/6) may be more convenient (Juniper et al. 1999, Juniper et al. 2005). Permission is required for use, which can be obtained here. Demonstration of poor symptom control on the ACQ-5 as an eligibility criterion for initial approval of omalizumab and mepolizumab treatment. A documented improvement in ACQ-5 score is required for continuing approvals for these medications. For more information see Medications – Monoclonal Antibodies

The Asthma Control Test (ACT) is short and easy to administer (Nathan et al. 2004, Schatz et al. 2009). It is recommended by Asthma Australia and the Australian Asthma Handbook as a useful tool to assess asthma symptom control in general practice. The ACT can be accessed here. Permission is required for use, which can be obtained here.

The Global Initiative for Asthma (GINA) assessment of asthma control uses four questions (GINA 2022). No permission is required to administer this questionnaire for clinical use.

Quality of life

The Asthma Quality of Life Questionnaire (AQLQ) is a 32-point questionnaire covering four domains; symptoms, activity limitation, emotional function, and environmental exposure (Juniper et al. 1999). Permission is required for use, which can be obtained here.

ACQ-5,6,7

(Five, six or seven-item Asthma Control Questionnaire)

 

ACT

(Asthma Control Test)

GINA

(Global Initiative for Asthma)

Age range ≥ 11 ≥ 12 ≥ 6
Questions 5, 6, or 6 + spirometry 5 4
Domains Nocturnal awakenings Limitation of activity Morning symptoms

Shortness of breath Wheezing

Reliever use (ACQ-6,7)

Spirometry (ACQ-7)

Activity limitation

Shortness of breath

Awakening

Reliever use

Self-assessed control

Daytime symptoms

Night time symptoms

Reliever use

Activity limitation

Duration Prior week Prior 4 weeks Prior 4 weeks
Scoring > 1.5 Poorly controlled

0.75-1.5 ‘Grey zone’

0-0.75 Well controlled

5-15 Very poorly controlled

16-19 Not well controlled

20-25 Well controlled

3-4 Uncontrolled

1-2 Partly controlled

0 Well controlled

MCID 0.5 3 –
Links Permission required from http://www.qoltech.co.uk/index.htm

 

https://asthma.org.au/about-asthma/understanding-asthma/asthma-control-test/

 

http://ginasthma.org/reports/

 

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Last Updated on October 3, 2022

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